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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP5
All Species:
25.45
Human Site:
S517
Identified Species:
40
UniProt:
Q8N3R9
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3R9
NP_071919.2
675
77294
S517
A
V
P
H
T
T
R
S
R
R
D
Q
E
V
A
Chimpanzee
Pan troglodytes
XP_510014
764
85553
S606
A
V
P
H
T
T
R
S
R
R
D
Q
E
V
A
Rhesus Macaque
Macaca mulatta
XP_001105724
674
77301
S516
A
V
P
H
T
T
R
S
R
R
D
Q
E
V
A
Dog
Lupus familis
XP_547862
675
77214
S517
A
V
P
H
T
T
R
S
R
R
D
H
E
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLB2
675
77211
N517
A
V
P
H
T
T
R
N
R
R
D
H
E
V
A
Rat
Rattus norvegicus
Q5U2Y3
576
65604
Y437
Q
N
N
K
F
I
E
Y
G
E
Y
K
N
N
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505475
675
76860
T517
A
V
P
H
T
T
R
T
R
R
D
N
E
V
A
Chicken
Gallus gallus
Q5ZJ00
468
52501
D332
K
N
E
V
D
G
K
D
Y
Y
F
V
S
T
E
Frog
Xenopus laevis
NP_001085267
675
76810
S517
A
V
P
H
T
T
R
S
R
R
E
N
E
V
S
Zebra Danio
Brachydanio rerio
Q8JHF4
677
76390
S519
P
V
P
H
T
T
R
S
R
R
D
A
E
A
N
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
E331
K
G
D
A
N
G
E
E
Y
F
F
I
S
N
E
Fruit Fly
Dros. melanogaster
Q24210
898
100893
P749
P
I
P
H
T
T
R
P
A
K
P
E
E
E
N
Honey Bee
Apis mellifera
XP_393395
1033
115664
P875
A
I
P
H
T
S
R
P
R
K
D
S
E
V
D
Nematode Worm
Caenorhab. elegans
P54936
961
108794
P812
P
I
P
H
T
T
R
P
P
R
K
D
E
V
D
Sea Urchin
Strong. purpuratus
XP_784409
971
107892
V813
A
V
P
H
T
T
R
V
M
K
E
H
E
I
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.6
97
98.2
N.A.
96.7
36.2
N.A.
93.7
25
86
77
25.7
26.7
34.7
24.1
34.7
Protein Similarity:
100
87.5
97.7
99.5
N.A.
98.6
54.9
N.A.
96.8
43.8
92.5
86.7
44.5
46.3
49.2
41.7
49.2
P-Site Identity:
100
100
100
93.3
N.A.
86.6
0
N.A.
86.6
0
80
73.3
0
40
60
53.3
53.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
6.6
N.A.
93.3
6.6
93.3
73.3
0
60
80
60
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
60
0
0
7
0
0
0
0
7
0
0
7
0
7
40
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
7
0
0
7
0
0
54
7
0
0
14
% D
% Glu:
0
0
7
0
0
0
14
7
0
7
14
7
80
7
14
% E
% Phe:
0
0
0
0
7
0
0
0
0
7
14
0
0
0
0
% F
% Gly:
0
7
0
0
0
14
0
0
7
0
0
0
0
0
0
% G
% His:
0
0
0
80
0
0
0
0
0
0
0
20
0
0
0
% H
% Ile:
0
20
0
0
0
7
0
0
0
0
0
7
0
7
0
% I
% Lys:
14
0
0
7
0
0
7
0
0
20
7
7
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
14
7
0
7
0
0
7
0
0
0
14
7
14
20
% N
% Pro:
20
0
80
0
0
0
0
20
7
0
7
0
0
0
0
% P
% Gln:
7
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% Q
% Arg:
0
0
0
0
0
0
80
0
60
60
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
7
0
40
0
0
0
7
14
0
7
% S
% Thr:
0
0
0
0
80
74
0
7
0
0
0
0
0
7
0
% T
% Val:
0
60
0
7
0
0
0
7
0
0
0
7
0
60
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
14
7
7
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _